Are some people more at genetic risk of abnormal bilirubin levels?
Several inherited conditions including Gilbert’s syndrome, Dubin-Johnson syndrome, Rotor’s syndrome and Crigler-Najjar syndrome can cause a raised bilirubin level. Of these four syndromes, Crigler-Najjar is the most serious. The first three are usually mild, long-term conditions that can be aggravated under certain conditions but in general cause no significant health problems.
How do you treat abnormal bilirubin levels and/or jaundice?
Treatment depends on the cause of the . In newborns, phototherapy (special light therapy), blood , and certain drugs may reduce the bilirubin level. In Gilbert’s, Rotor’s and Dubin-Johnson syndrome, no treatment is usually necessary. Crigler-Najjar syndrome may respond to certain drug therapy or may require a liver transplant. Jaundice caused by an obstruction, for example gallstones, is often resolved by surgery to remove the blockage. Jaundice due to is often a result of long-term alcohol abuse and may not respond well to any type of therapy, though abstaining from alcohol and ensuring good nutrition may improve the situation if the liver has not been damaged too badly.
Is there anything I can do to maintain healthy bilirubin levels?
While there is no one specific thing, it is clear that excessive and long term alcohol consumption can lead to and a permanently damaged liver. Avoiding excessive alcohol consumption, drug and eating a proper diet can help sustain a healthy liver.
What are the signs and symptoms of increased bilirubin levels?
The presence of , dark urine, pale stools and generalised itching may be found in obstructive jaundice. More severe cases may include severe abdominal pain, anorexia, vomiting and fever. Increased bilirubin levels may be a sign of another problem, such as cancer, and may be seen in conjunction with swollen glands or an enlarged spleen.