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Symptoms of Cushing's syndrome

The signs and symptoms that occur with Cushing’s syndrome depend on a number of factors that include the cause of the Cushing’s syndrome, the level of cortisol or ACTH, the age and sex of the patient.

They include:

  • obesity around the waist and also fat laid down across the shoulders and neck; arms and legs tend to be thin
  • the face may be round and flushed
  • bruising is commonly present especially on the legs
  • wounds may heal very slowly
  • there may be muscle weakness
  • tiredness
  • ‘stretch’ marks around the stomach, hips and thighs
  • pigmentation of the skin, particularly of scars and inside the mouth
  • thin fragile skin that bruises easily
  • raised blood pressure (hypertension)
  • raised blood sugar (diabetes)
  • fragile bones (osteoporosis)
  • women usually have menstrual irregularities

Last Review Date: April 5, 2017