Lab Tests Online - Explaining Pathology

Glossary

Gene rearrangement


Gene rearrangement - chromosomal rearrangement is a type of mutation. It is a chromosome abnormality involving a change in the structure of the chromosome. Usually, these events are caused by a breakage in the DNA strands at two different locations, followed by a rejoining of the broken ends to produce a new chromosomal arrangement of genes, different from the gene order of the chromosomes before they were broken.