| Endocrine gland |
Location/ description |
Hormones produced by gland |
Gland/ hormone function |
Examples of disorders associated with improper function |
| Hypothalamus |
Lower middle of the brain |
Growth hormone-releasing hormone (GHRH Thyrotropin-releasing hormone (TRH) Corticotropin-releasing hormone (CRH) Gonadotropin-releasing hormone (GnRH Prolactin inhibitory factor (PIF, dopamine) |
Communicates with both nervous and endocrine systems; Stimulates (GHRH, TRH, CRH, GnRH) or inhibits (PIF) hormone production in the pituitary |
Precocious puberty (early GnRH production); Kallman syndrome (inadequate GnRH production); Thyroid diseases |
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Oxytocin |
Uterine contraction during labour |
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Arginine vasopressin (AVP), also called antidiurectic hormone (ADH) |
Water balance |
Diabetes insipidus (inadequate AVP production) |
| Pituitary |
Below hypothalamus, behind sinus cavity |
Prolactin |
Milk production |
Hypopituitarism Empty Sella syndrome Galactorrhoea (milk production not during pregnancy due to high prolactin) |
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Growth hormone (GH) |
Bone growth |
Acromegaly or Gigantism (excess GH) |
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ACTH |
Stimulates cortisol |
Cushing's disease (excess ACTH) |
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TSH |
Stimulates thyroid hormone |
Hyperthyroidism Hypothyroidism |
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LH, FSH |
Regulation of testosterone and oestrogen, fertility |
Loss of menstrual period Loss of sex drive Infertility |
| Thyroid |
Butterfly-shaped; lies flat against windpipe in the throat |
T4 (thyroxine) T3 (triiodothyronine) |
Helps regulate the rate of metabolism |
Thyroid diseases |
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Calcitonin |
Helps regulate bone status, blood calcium |
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| Parathyroid |
4 tiny glands located behind, next to, or below the thyroid |
Parathyroid hormone (PTH) |
Regulates blood calcium |
Hyperparathyroidism Hypoparathyroidism MEN1 |
| Adrenal |
2 triangular organs, on top of each kidney |
Adrenaline Noradrenaline |
Blood pressure regulation, stress reaction |
Phaeochromocytoma (MEN2) |
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Aldosterone |
Salt, water balance |
Conn's syndrome |
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Cortisol |
Stress reaction |
Cushing's syndrome Addison's disease |
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DHEA-S |
Body hair development at puberty |
Cancer Adrenal hyperplasia |
Ovaries (females only) |
2 located in the pelvis |
Oestrogen Progesterone |
Female sexual characteristics |
Polycystic ovary syndrome (PCOS) |
Testes (males only) |
2 located in the groin |
Testosterone |
Male sexual characteristics |
Hypogonadism |
| Pancreas |
Large, gourd-shaped gland, located behind the stomach |
Insulin Glucagon Somatostatin |
Glucose regulation |
Diabetes mellitus MENI Zollinger-Ellison syndrome |
| Pineal |
Lower side of the brain |
Melatonin |
Not well understood; Helps control sleep patterns, affects reproduction |
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